The cellular architecture of the antimicrobial response network in human leprosy granulomas
Granulomas are complex cellular structures composed predominantly of macrophages and lymphocytes that function to contain and kill invading pathogens. Here, we investigated the single-cell phenotypes associated with antimicrobial responses in human leprosy granulomas by applying single-cell and spat...
Main Authors: | Ma, Feiyang, Hughes, Travis K, Teles, Rosane MB, Andrade, Priscila R, de Andrade Silva, Bruno J, Plazyo, Olesya, Tsoi, Lam C, Do, Tran, Wadsworth, Marc H, Oulee, Aislyn, Ochoa, Maria Teresa, Sarno, Euzenir N, Iruela-Arispe, M Luisa, Klechevsky, Eynav, Bryson, Bryan, Shalek, Alex K, Bloom, Barry R, Gudjonsson, Johann E, Pellegrini, Matteo, Modlin, Robert L |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2023
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Online Access: | https://hdl.handle.net/1721.1/147779 |
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