Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies

Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies

<jats:title>Abstract</jats:title><jats:p>Antibiotic tolerance, or the ability of bacteria to survive antibiotic treatment in the absence of genetic resistance, has been linked to chronic and recurrent infections. Tolerant cells are often characterized by a low metabolic state, agai...

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Bibliographic Details
Main Authors: Zheng, Erica J, Andrews, Ian W, Grote, Alexandra T, Manson, Abigail L, Alcantar, Miguel A, Earl, Ashlee M, Collins, James J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147786

Internet

https://hdl.handle.net/1721.1/147786

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