SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates

<jats:title>Abstract</jats:title> <jats:p>SETDB1 is a key regulator of lineage-specific genes and endogenous retroviral elements (ERVs) through its deposition of repressive H3K9me3 mark. Apart from its H3K9me3 regulatory role, SETDB1 has seldom been studied in terms...

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Detalhes bibliográficos
Principais autores: Warrier, Tushar, El Farran, Chadi, Zeng, Yingying, Ho, Benedict Shao Quan, Bao, Qiuye, Zheng, Zi Hao, Bi, Xuezhi, Ng, Huck Hui, Ong, Derrick Sek Tong, Chu, Justin Jang Hann, Sanyal, Amartya, Fullwood, Melissa Jane, Collins, James J, Li, Hu, Xu, Jian, Loh, Yuin-Han
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:English
Publicado em: Oxford University Press (OUP) 2023
Acesso em linha:https://hdl.handle.net/1721.1/147787