Reeling it in: how DNA topology drives loop extrusion by condensin
Structural maintenance of chromosomes (SMC) complexes such as condensin regulate chromosome organization by extruding loops. A new study uses single-molecule imaging of condensin on supercoiled DNA to understand how condensins navigate the under- and overwound DNA states common throughout the genome...
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2023
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Online Access: | https://hdl.handle.net/1721.1/147832 |