Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1

Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1

<jats:title>Abstract</jats:title><jats:p>It remains unclear why acute depletion of CTCF (CCCTC-binding factor) and cohesin only marginally affects expression of most genes despite substantially perturbing three-dimensional (3D) genome folding at the level of domains and structural...

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Bibliographic Details
Main Authors: Hsieh, Tsung-Han S, Cattoglio, Claudia, Slobodyanyuk, Elena, Hansen, Anders S, Darzacq, Xavier, Tjian, Robert
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147833

Internet

https://hdl.handle.net/1721.1/147833

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