STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
<jats:title>Abstract</jats:title><jats:p>Activation of the innate immune STimulator of INterferon Genes (STING) pathway potentiates antitumour immunity, but systemic delivery of STING agonists to tumours is challenging. We conjugated STING-activating cyclic dinucleotides (CDNs) to...
Hauptverfasser: | , , , , , , , , , , , , , , , , |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
Springer Science and Business Media LLC
2023
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Online Zugang: | https://hdl.handle.net/1721.1/147842 |