Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models

Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models

Functional precision medicine aims to match individual cancer patients to optimal treatment through ex vivo drug susceptibility testing on patient-derived cells. However, few functional diagnostic assays have been validated against patient outcomes at scale because of limitations of such assays. Her...

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Bibliographic Details
Main Authors: Stockslager, Max A, Malinowski, Seth, Touat, Mehdi, Yoon, Jennifer C, Geduldig, Jack, Mirza, Mahnoor, Kim, Annette S, Wen, Patrick Y, Chow, Kin-Hoe, Ligon, Keith L, Manalis, Scott R
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/147876

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https://hdl.handle.net/1721.1/147876

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