Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models
Functional precision medicine aims to match individual cancer patients to optimal treatment through ex vivo drug susceptibility testing on patient-derived cells. However, few functional diagnostic assays have been validated against patient outcomes at scale because of limitations of such assays. Her...
Main Authors: | Stockslager, Max A, Malinowski, Seth, Touat, Mehdi, Yoon, Jennifer C, Geduldig, Jack, Mirza, Mahnoor, Kim, Annette S, Wen, Patrick Y, Chow, Kin-Hoe, Ligon, Keith L, Manalis, Scott R |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2023
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Online Access: | https://hdl.handle.net/1721.1/147876 |
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