Prioritization of Molecular Targets for Antimalarial Drug Discovery

There is a shift in antimalarial drug discovery from phenotypic screening toward target-based approaches, as more potential drug targets are being validated in Plasmodium species. Given the high attrition rate and high cost of drug discovery, it is important to select the targets most likely to deli...

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Main Authors: Forte, Barbara, Ottilie, Sabine, Plater, Andrew, Campo, Brice, Dechering, Koen J, Gamo, Francisco Javier, Goldberg, Daniel E, Istvan, Eva S, Lee, Marcus, Lukens, Amanda K, McNamara, Case W, Niles, Jacquin C, Okombo, John, Pasaje, Charisse Flerida A, Siegel, Miles G, Wirth, Dyann, Wyllie, Susan, Fidock, David A, Baragaña, Beatriz, Winzeler, Elizabeth A, Gilbert, Ian H
其他作者: Massachusetts Institute of Technology. Department of Biological Engineering
格式: Article
語言:English
出版: American Chemical Society (ACS) 2023
在線閱讀:https://hdl.handle.net/1721.1/147890