Mapping and modeling macrophages in tuberculosis
Immune cells polarize to diverse transcriptional and functional states to cause or resolve disease. Understanding this cellular diversity is critical to identifying new clinical interventions. Macrophages in tuberculosis granulomas are an archetype of these phenomena. Pinpointing the cellular states...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/147899 |