Mapping and modeling macrophages in tuberculosis

Immune cells polarize to diverse transcriptional and functional states to cause or resolve disease. Understanding this cellular diversity is critical to identifying new clinical interventions. Macrophages in tuberculosis granulomas are an archetype of these phenomena. Pinpointing the cellular states...

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Bibliographic Details
Main Author: Peters, Joshua M.
Other Authors: Bryson, Bryan D.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/147899