Synthetic biology tools for sensing and evolving microbes: CRISPR-diagnostics and transposon-mediated genome re-wiring
Mobile genetic elements (MGEs) have played a fundamental role in the evolution of complex organisms, driving innovation through competition, collaboration and co-option. Transposons, in particular, are an ancient family of MGEs whose diverse functions have provided a rich source of DNA-binding and n...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2023
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| Online Access: | https://hdl.handle.net/1721.1/147906 |