Host-derived O-glycans inhibit toxigenic conversion by a virulence-encoding phage in Vibrio cholerae

Host-derived O-glycans inhibit toxigenic conversion by a virulence-encoding phage in Vibrio cholerae

Pandemic and endemic strains of Vibrio cholerae arise from toxigenic conversion by the CTXφ bacteriophage, a process by which CTXφ infects nontoxigenic strains of V. cholerae. CTXφ encodes the cholera toxin, an enterotoxin responsible for the watery diarrhea associated with cholera infections. Despi...

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Bibliographic Details
Main Authors: Wang, Benjamin X, Takagi, Julie, McShane, Abigail, Park, Jin Hwan, Aoki, Kazuhiro, Griffin, Catherine, Teschler, Jennifer, Kitts, Giordan, Minzer, Giulietta, Tiemeyer, Michael, Hevey, Rachel, Yildiz, Fitnat, Ribbeck, Katharina
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: EMBO 2023
Online Access:https://hdl.handle.net/1721.1/147918

Internet

https://hdl.handle.net/1721.1/147918

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