A synthetic distributed genetic multi-bit counter

A design for genetically encoded counters is proposed via repressor-based circuits. An N-bit counter reads sequences of input pulses and displays the total number of pulses, modulo 2 N . The design is based on distributed computation with specialized cell types allocated to specific tasks. This a...

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Bibliographic Details
Main Authors: Chen, Tianchi, Ali Al-Radhawi, M, Voigt, Christopher A, Sontag, Eduardo D
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/147930