A synthetic transcription platform for programmable gene expression in mammalian cells

A synthetic transcription platform for programmable gene expression in mammalian cells

<jats:title>Abstract</jats:title><jats:p>Precise, scalable, and sustainable control of genetic and cellular activities in mammalian cells is key to developing precision therapeutics and smart biomanufacturing. Here we create a highly tunable, modular, versatile CRISPR-based synthet...

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Bibliographic Details
Main Authors: Chen, William CW, Gaidukov, Leonid, Lai, Yong, Wu, Ming-Ru, Cao, Jicong, Gutbrod, Michael J, Choi, Gigi CG, Utomo, Rachel P, Chen, Ying-Chou, Wroblewska, Liliana, Kellis, Manolis, Zhang, Lin, Weiss, Ron, Lu, Timothy K
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147941

Internet

https://hdl.handle.net/1721.1/147941

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