Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants

Absolute quantification of tumor antigens using embedded MHC-I isotopologue calibrants

<jats:p>Absolute quantification measurements (copies per cell) of peptide major histocompatibility complex (pMHC) antigens are necessary to inform targeted immunotherapy drug design; however, existing methods for absolute quantification have critical limitations. Here, we present a platform te...

Full description

Bibliographic Details
Main Authors: Stopfer, Lauren E, Gajadhar, Aaron S, Patel, Bhavin, Gallien, Sebastien, Frederick, Dennie T, Boland, Genevieve M, Sullivan, Ryan J, White, Forest M
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2023
Online Access:https://hdl.handle.net/1721.1/147945

Internet

https://hdl.handle.net/1721.1/147945

Similar Items