Mathematical analysis of the limiting behaviors of a chromatin modification circuit

Abstract In the last decade, the interactions among histone modifications and DNA methylation and their effect on the DNA structure, i.e., chromatin state, have been identified as key mediators for the maintenance of cell identity, defined as epigenetic cell memory. In this paper, we de...

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Bibliographic Details
Main Authors: Bruno, Simone, Williams, Ruth J., Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Springer London 2023
Online Access:https://hdl.handle.net/1721.1/148029