Yeast Display for the Identification of Peptide-MHC Ligands of Immune Receptors

T cells detect peptide antigens presented by major histocompatibility complex (MHC) proteins via their T cell receptor (TCR). The sequence diversity of possible antigens, with trillions of potential peptide-MHC targets, makes it challenging to study, characterize, and manipulate the peptide repertoi...

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Bibliographic Details
Main Authors: Huisman, Brooke D, Grace, Beth E, Holec, Patrick V, Birnbaum, Michael E
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer US 2023
Online Access:https://hdl.handle.net/1721.1/148130