Guanidinium Compounds: Synthesis, Oxoanion Binding, and Cellular Delivery

The delivery of biological molecules into cells has been an issue of importance in both chemical biology and drug discovery. One method used to transport biologics into cells is the cellpenetrating peptide (CPP). This arginine-rich peptide forms strong interactions with the cell surface through bide...

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Bibliographic Details
Main Author: Orgren Calabretta, Lindsey
Other Authors: Raines, Ronald T.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/148290