The impact of intratumor heterogeneity on anti-tumor immunity
Cancer immunotherapies, notably checkpoint blockade therapy (CBT), have proven efficacy to control cancer growth, with a fraction of patients exhibiting durable responses. However, the majority of patients do not respond to CBT and the molecular determinants of resistance have not been fully charact...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/150240 https://orcid.org/0000-0002-2269-6809 |