Feedforward growth rate control mitigates gene activation burden

Feedforward growth rate control mitigates gene activation burden

<jats:title>Abstract</jats:title><jats:p>Heterologous gene activation causes non-physiological burden on cellular resources that cells are unable to adjust to. Here, we introduce a feedforward controller that actuates growth rate upon activation of a gene of interest (GOI) to compe...

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Bibliographic Details
Main Authors: Barajas, Carlos, Huang, Hsin-Ho, Gibson, Jesse, Sandoval, Luis, Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/150903

Internet

https://hdl.handle.net/1721.1/150903

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