Patterns and processes driving chromosome organization

In this thesis, we focus on different approaches to studying the organization of chro­mosomes with in the nucleus of cells. We employ both genomic analysis of chromo­some interaction maps, and polymer simulations to answer various questions that are relevant to the field. The first two chapters o...

Full description

Bibliographic Details
Main Author: Abraham, Sameer
Other Authors: Mirny, Leonid A.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/150915