Development of Dendritic Polymers as a Modular Drug Delivery Platform for Avascular Tissues
Avascular tissues, such as articular cartilage, meniscus, intervertebral discs, and cornea stroma, pose a number of challenges for disease treatment. Systemic therapies will not reach the target tissue at efficacious levels. Local therapies are rapidly cleared from the tissue due to turnover of biol...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/151302 |