The Heparan Sulfate Proteoglycan Perlecan Regulates Axonal and Synaptic Stability
Heparan sulfate proteoglycans (HSPGs) form essential components of the extracellular matrix (ECM) and basement membrane (BM) and have both structural and signaling roles. Perlecan is a secreted ECM-localized HSPG that contributes to tissue integrity and cell-cell communication. In this thesis, I ide...
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Massachusetts Institute of Technology
2023
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| Online Access: | https://hdl.handle.net/1721.1/151363 https://orcid.org/0000-0002-2579-8712 |