The Heparan Sulfate Proteoglycan Perlecan Regulates Axonal and Synaptic Stability

The Heparan Sulfate Proteoglycan Perlecan Regulates Axonal and Synaptic Stability

Heparan sulfate proteoglycans (HSPGs) form essential components of the extracellular matrix (ECM) and basement membrane (BM) and have both structural and signaling roles. Perlecan is a secreted ECM-localized HSPG that contributes to tissue integrity and cell-cell communication. In this thesis, I ide...

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Bibliographic Details
Main Author:	Guss, Ellen Jane
Other Authors:	Littleton, J. Troy
Format:	Thesis
Published:	Massachusetts Institute of Technology 2023
Online Access:	https://hdl.handle.net/1721.1/151363 https://orcid.org/0000-0002-2579-8712

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