Protein-based Degrader Strategies against Oncogenic RAS

Targeted therapies have emerged as a promising cancer treatment strategy by inhibiting proteins specific to cancer cells while preserving healthy cells. RAS proteins play a crucial role in cancer development and are associated with increased tumor growth and invasion. Mutations in RAS genes, especia...

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Bibliographic Details
Main Author: Cheah, Keith M.
Other Authors: Wittrup, K. Dane
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/151504