Insights into the substrate specificities, interactions and regulatory mechanisms of bacterial glycoconjugate biosynthesis enzymes

Monotopic phosphoglycosyl transferase enzymes (MonoPGTs) are membrane-bound enzymes that initiate the assembly of prokaryotic glycoconjugates essential for bacterial survival and proliferation. MonoPGTs belong to an expansive superfamily with a diverse and richly annotated sequence space; however, l...

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Bibliographic Details
Main Author: Anderson, Alyssa J.
Other Authors: Imperiali, Barbara
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/151506