A Selection for Intein Splicing inPhage Assisted Continuous Evolution

Developing tools for target manipulation of protein chemistry remains a longstanding goal in chemical biology. Trans-splicing inteins fulfill a crucial niche in this area by enabling post translational splicing of separate polypeptides, introduction of post translational modifications, and other che...

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Bibliographic Details
Main Author: Hennes, Andrew
Other Authors: Wang, Xiao
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/151530