Correlation-based Linking of Epigenomic Regions to Target Genes in Bulk and Single Cell Epigenomic Data
Single-cell sequencing has catalyzed a significant shift in biological modeling and hypothesis generation. In this study, we present advanced algorithms that utilize multiple modalities for peak-gene linking via correlation-based mechanisms. This approach provides a robust framework for bias correct...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/151538 |