Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells

High-grade serous ovarian cancer (HGSOC) is responsible for the majority of gynecology cancer-related deaths. Patients in remission often relapse with more aggressive forms of disease within 2 years post-treatment. Alternative immuno-oncology (IO) strategies, such as immune checkpoint blockade (ICB)...

Full description

Bibliographic Details
Main Authors: Gerton, Thomas J., Green, Allen, Campisi, Marco, Chen, Minyue, Gjeci, Iliana, Mahadevan, Navin, Lee, Catherine A. A., Mishra, Ranjan, Vo, Ha V., Haratani, Koji, Li, Ze-Hua, Hasselblatt, Kathleen T., Testino, Bryanna, Connor, Trevor, Lian, Christine G., Elias, Kevin M., Lizotte, Patrick, Ivanova, Elena V., Barbie, David A., Dinulescu, Daniela M.
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2023
Online Access:https://hdl.handle.net/1721.1/152071