Automated Flow Synthesis of Biomacromolecules
Chemically synthesized biomacromolecules are powerful tools that enable modern biological study, but certain classes remain under-investigated. Existing techniques to access phosphorodiamidate morpholino oligomers (PMOs), mirror image proteins (D proteins), and peptide nucleic acids (PNAs) are funct...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2023
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| Online Access: | https://hdl.handle.net/1721.1/152125 |