Advances in Sensitivity and Resolution of Solid State Nuclear Magnetic Resonance and Dynamic Nuclear Polarization
Traditional structural biology methods such as x-ray crystallography and solution-state nuclear magnetic resonance (NMR) cannot provide atomic level resolution of insoluble, noncrystalline proteins. Such proteins include amyloid fibrils implicated in numerous neurodegenerative diseases. While solid...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Published: |
Massachusetts Institute of Technology
2023
|
| Online Access: | https://hdl.handle.net/1721.1/152131 |