SCA: recovering single-cell heterogeneity through information-based dimensionality reduction
Abstract Dimensionality reduction summarizes the complex transcriptomic landscape of single-cell datasets for downstream analyses. Current approaches favor large cellular populations defined by many genes, at the expense of smaller and more subtly defined populations. Here, we present...
Main Authors: | DeMeo, Benjamin, Berger, Bonnie |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | English |
Published: |
BioMed Central
2023
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Online Access: | https://hdl.handle.net/1721.1/152252 |
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