Dynamics of Genome Organization

A human cell contains about 2m of DNA, packed into a nucleus with diameter ~10μm. The three-dimensional structure of this packing has been the subject of intense investigation essentially since the discovery of DNA itself, with an explosion of the field over the past 15 years, following the advent o...

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Bibliographic Details
Main Author: Grosse-Holz, Simon Benedikt
Other Authors: Mirny, Leonid A.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/152570