Siderophore-Based Drug Repurposing of Platinum Anticancer Agents as Targeted Antibiotics and Investigation of Pt-Induced DNA Damage in Gram-Negative Bacteria

Bacterial infections are a growing threat to human health. This crisis has been exacerbated by the overuse of broad-spectrum antibiotics, resulting in adverse consequences such as the rapid emergence and spread of antibiotic resistance. Additionally, the use of broad-spectrum antibiotics disrupts th...

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Bibliographic Details
Main Author: Guo, Chuchu
Other Authors: Nolan, Elizabeth M.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/153027
https://orcid.org/0000-0002-1500-3621