Improving Cardiac Delivery of Antisense Oligonucleotides with Peptidomimetic Targeting Agents

Cardiovascular disease (CVD) is one of the leading causes of death worldwide, both individually and as a comorbidity for other diseases such as diabetes and atherosclerosis. Unfortunately, CVD trends irreversibly toward heart failure. Current treatments only manage symptoms such as high blood pressu...

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Bibliographic Details
Main Author: Antilla, Sarah An-ning
Other Authors: Pentelute, Bradley L.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/153070