Dissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics

Cancer is a disease that undergoes selective pressure to evolve during its progression, becoming increasingly heterogeneous. Tumoral heterogeneity can dictate therapeutic response. Transcriptomics can be used to uncover complexities in cancer and reveal phenotypic heterogeneity that affects disease...

Full description

Bibliographic Details
Main Authors: Liu, Wendi, Puri, Anusha, Fu, Doris, Chen, Lee, Wang, Cassia, Kellis, Manolis, Yang, Jiekun
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Springer Netherlands 2023
Online Access:https://hdl.handle.net/1721.1/153162