Beta-Hydroxybutyrate Augments Oxaliplatin-Induced Cytotoxicity by Altering Energy Metabolism in Colorectal Cancer Organoids

Deregulation of cellular metabolism has recently emerged as a notable cancer characteristic. This reprogramming of key metabolic pathways supports tumor growth. Targeting cancer metabolism demonstrates the potential for managing colorectal cancer. Beta-hydroxybutyrate (BOHB) acts as an acetyl-CoA so...

Full description

Bibliographic Details
Main Authors: Sever, Tolga, Ellidokuz, Ender Berat, Basbinar, Yasemin, Ellidokuz, Hulya, Yilmaz, Ömer H., Calibasi-Kocal, Gizem
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2023
Online Access:https://hdl.handle.net/1721.1/153248