Tool Development for Studying and Manipulating Peptide-MHC Interactions in a Globally-Representative Manner

Major histocompatibility complex (MHC) proteins play a critical role in the adaptive immune system, presenting peptide fragments on the surface of cells for surveillance by T cells. In this way, T cells are able to sense cellular dysfunction associated with disease, such as the presence of pathogen-...

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Bibliographic Details
Main Author: Huisman, Brooke D.
Other Authors: Birnbaum, Michael E.
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/153466
https://orcid.org/0000-0002-6229-6498