Tool Development for Studying and Manipulating Peptide-MHC Interactions in a Globally-Representative Manner
Major histocompatibility complex (MHC) proteins play a critical role in the adaptive immune system, presenting peptide fragments on the surface of cells for surveillance by T cells. In this way, T cells are able to sense cellular dysfunction associated with disease, such as the presence of pathogen-...
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Format: | Thesis |
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Massachusetts Institute of Technology
2024
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Online Access: | https://hdl.handle.net/1721.1/153466 https://orcid.org/0000-0002-6229-6498 |