Understanding the Differential Effects of Dexamethasone on the Metabolism of Healthy and Diseased Articular Cartilage

The glucocorticoid drug Dexamethasone (Dex) has been proposed as a potential therapeutic to treat or prevent post-traumatic osteoarthritis (PTOA), a disease affecting millions of Americans without a disease-modifying drug. However, current reports on Dex efficacy often disagree on the effects of Dex...

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Bibliographic Details
Main Author: Black, Rebecca M.
Other Authors: Grodzinsky, Alan J.
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/153473