Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD

Targeted therapies are effective cancer treatments when accompanied by accurate diagnostic tests that can help identify patients that will respond to those therapies. The YAP/TAZ-TEAD axis is activated and plays a causal role in several cancer types, and TEAD inhibitors are currently in early-phase...

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Detalhes bibliográficos
Main Authors: Kanai, Ryan, Norton, Emily, Stern, Patrick, Hynes, Richard O., Lamar, John M.
Outros Autores: Koch Institute for Integrative Cancer Research at MIT
Formato: Artigo
Publicado em: MDPI AG 2024
Assuntos:
Acesso em linha:https://hdl.handle.net/1721.1/153660