Computational Study of Vaccination Strategies to Change B Cell Immunodominance

B cell Immunodominance refers to the phenomenon where B cells that target certain epitopes of a pathogen are preferentially selected among the B cells that potentially target diverse epitopes presented on a pathogenic protein. This phenomenon presents a challenge in the development of vaccines again...

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Bibliographic Details
Main Author: Yang, Leerang
Other Authors: Chakraborty, Arup K.
Format: Thesis
Published: Massachusetts Institute of Technology 2024
Online Access:https://hdl.handle.net/1721.1/153691