Engineering minimally immunogenic cargos and delivery modalities for gene therapy
Since the discovery of CRISPR-Cas9 systems, gene therapies have revolutionized the field of molecular biology by introducing functional genes into cells to correct genetic defects or diseases. To date, several gene therapies are pending approval for use in the clinic and have shown promise in the tr...
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Format: | Thesis |
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Massachusetts Institute of Technology
2024
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Online Access: | https://hdl.handle.net/1721.1/153703 |