Engineering minimally immunogenic cargos and delivery modalities for gene therapy
Since the discovery of CRISPR-Cas9 systems, gene therapies have revolutionized the field of molecular biology by introducing functional genes into cells to correct genetic defects or diseases. To date, several gene therapies are pending approval for use in the clinic and have shown promise in the tr...
Main Author: | Raghavan, Rumya S. |
---|---|
Other Authors: | Zhang, Feng |
Format: | Thesis |
Published: |
Massachusetts Institute of Technology
2024
|
Online Access: | https://hdl.handle.net/1721.1/153703 |
Similar Items
-
Hollow mesoporous silica nanoparticles for sustained cargo delivery
by: Ling, Hwee Ting.
Published: (2012) -
Axonal membrane trafficking regulation and its failure in cargo delivery
by: Chaiamarit, T
Published: (2023) -
Cargo delivery into gram-negative bacteria via enterobactin uptake machinery
by: Zheng, Tengfei
Published: (2014) -
Preventing the immunogenicity of biological therapies
by: Somerfield, J, et al.
Published: (2011) -
Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds and Evaluation of Enterobactin-Cargo Conjugate Uptake
by: Zheng, Tengfei, et al.
Published: (2014)