Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

Background B-type lamins are critical nuclear envelope proteins that interact with the three-dimensional genomic architecture. However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joint depletion severely impacts cell viabili...

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Bibliographic Details
Main Authors: Pujadas Liwag, Emily M., Wei, Xiaolong, Acosta, Nicolas, Carter, Lucas M., Yang, Jiekun, Almassalha, Luay M., Jain, Surbhi, Daneshkhah, Ali, Rao, Suhas S. P., Seker-Polat, Fidan, MacQuarrie, Kyle L., Ibarra, Joe, Agrawal, Vasundhara, Aiden, Erez Lieberman, Kanemaki, Masato T., Backman, Vadim, Adli, Mazhar
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2024
Online Access:https://hdl.handle.net/1721.1/153927

Internet

https://hdl.handle.net/1721.1/153927

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