Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses
Consistent with the biochemistry of coronaviruses as well established over decades, SARS-CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) to sialylated glycans (containing the monosaccharide sialic acid) on the cell surface. The virus can then slide over...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
MDPI AG
2024
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| Online Access: | https://hdl.handle.net/1721.1/154298 |