Ketamine can produce oscillatory dynamics by engaging mechanisms dependent on the kinetics of NMDA receptors

Ketamine is an N-methyl-D-aspartate (NMDA)-receptor antagonist that produces sedation, analgesia, and dissociation at low doses and profound unconsciousness with antinociception at high doses. At high and low doses, ketamine can generate gamma oscillations (>25 Hz) in the electroencephalogram...

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Bibliographic Details
Main Authors: Adam, Elie, Kowalski, Marek, Akeju, Oluwaseun, Miller, Earl K., Brown, Emery N., McCarthy, Michelle M., Kopell, Nancy
Other Authors: Picower Institute for Learning and Memory
Format: Article
Published: Proceedings of the National Academy of Sciences 2024
Online Access:https://hdl.handle.net/1721.1/155039