RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

Oral drug delivery of proteins is limited by the degradative environment of the gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs. Luminal mucus represents the initial steric and dynamic barrier to absorption. To overcome this barrier, we report the devel...

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Bibliographic Details
Main Authors: Srinivasan, Shriya S., Alshareef, Amro, Hwang, Alexandria V., Kang, Ziliang, Kuosmanen, Johannes, Ishida, Keiko, Jenkins, Joshua, Liu, Sabrina, Madani, Wiam Abdalla Mohammed, Lennerz, Jochen, Hayward, Alison, Morimoto, Josh, Fitzgerald, Nina, Langer, Robert, Traverso, Giovanni
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science 2024
Online Access:https://hdl.handle.net/1721.1/155042

Internet

https://hdl.handle.net/1721.1/155042

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