Recurrent Glioblastoma—Molecular Underpinnings and Evolving Treatment Paradigms

Glioblastoma is the most common and lethal central nervous system malignancy with a median survival after progression of only 6–9 months. Major biochemical mechanisms implicated in glioblastoma recurrence include aberrant molecular pathways, a recurrence-inducing tumor microenvironment, an...

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Bibliographic Details
Main Authors: Chang, Christopher, Chavarro, Velina S., Gerstl, Jakob V. E., Blitz, Sarah E., Spanehl, Lennard, Dubinski, Daniel, Valdes, Pablo A., Tran, Lily N., Gupta, Saksham, Esposito, Luisa, Mazzetti, Debora, Gessler, Florian A., Arnaout, Omar, Smith, Timothy R., Friedman, Gregory K., Peruzzi, Pierpaolo, Bernstock, Joshua D.
Format: Article
Published: MDPI AG 2024
Online Access:https://hdl.handle.net/1721.1/155435