Recurrent Glioblastoma—Molecular Underpinnings and Evolving Treatment Paradigms

Glioblastoma is the most common and lethal central nervous system malignancy with a median survival after progression of only 6–9 months. Major biochemical mechanisms implicated in glioblastoma recurrence include aberrant molecular pathways, a recurrence-inducing tumor microenvironment, an...

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Detalhes bibliográficos
Principais autores: Chang, Christopher, Chavarro, Velina S., Gerstl, Jakob V. E., Blitz, Sarah E., Spanehl, Lennard, Dubinski, Daniel, Valdes, Pablo A., Tran, Lily N., Gupta, Saksham, Esposito, Luisa, Mazzetti, Debora, Gessler, Florian A., Arnaout, Omar, Smith, Timothy R., Friedman, Gregory K., Peruzzi, Pierpaolo, Bernstock, Joshua D.
Outros Autores: Koch Institute for Integrative Cancer Research at MIT
Formato: Artigo
Publicado em: MDPI AG 2024
Acesso em linha:https://hdl.handle.net/1721.1/155435