Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome

Mesenchymal stem and stromal cells (MSCs) hold potential to treat a broad range of clinical indications, but clinical translation has been limited to date due in part to challenges with batch-to-batch reproducibility of potential critical quality attributes (pCQAs) that can predict potency/efficacy....

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Bibliographic Details
Main Authors: Krupczak, Brandon, Farruggio, Camille, Van Vliet, Krystyn J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2024
Online Access:https://hdl.handle.net/1721.1/155578